Organic Process Research and Development p. 1372 - 1376 (2014)
Update date:2022-08-30
Topics:
Itabaiana, Ivaldo
Gonalves, Karen M.
Zoumpanioti, Maria
Leal, Ivana C. R.
Miranda, Leandro S. M. E
Xenakis, Aristotelis
De Souza, Rodrigo O. M. A.
In this work, microemulsion-based organogels (MBGs) containing lipase are reported as an efficient catalytic system for monoacylglyceride (MAG) synthesis. More specifically, Candida antarctica lipase B (CaLB) was immobilized on an MBG matrix (MBGCaLB) formed with (hydroxypropyl)methyl cellulose as a gelling agent, and this catalyst revealed high conversion yields (expressed in grams of ester per hour per gram of enzyme) under both batch and continuous-flow conditions. Under flow conditions, 1:1 stearic acid/solketal (100 mM in n-heptane) could be converted to protected MAG (>99%) in a residence time of 11 min at 45 °C. A recycle study showed that the MBGCaLB system can be recycled 15 times without activity loss, a number 2 times higher than under batch conditions catalyzed by immobilized lipase, in agreement with green chemistry protocols.
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Doi:10.1021/jo00981a007
(1972)Doi:10.1016/0040-4020(95)00509-7
(1995)Doi:10.1002/asia.201800938
(2018)Doi:10.1021/ja01269a047
(1938)Doi:10.1021/ic50043a012
(1966)Doi:10.1039/c3cc46720a
(2013)