SYNTHESE A L'AIDE DE SULFONES-XXVI. SYNTHESE D'ALCOOLS ALLYLIQUES ET DE POLYPRENOLS PAR ATTACHEMENT D'UN SYNTHON PRENOL EN POSITION 4 E

Article abstract of DOI:10.1016/S0040-4020(01)91578-9

The E-hydroxyalkylsulphone PhSO2CH2C(CH3)=CHCH2OH is regioselectively and stereoselectively substituted by Grignard reagents in the presence of copper(II) acetylacetonate, giving E allylic alcohols in high yield.A recurrent synthesis of polyprenols and an efficient preparation of the African Monarch pheromone are described.