Tetrahedron Letters p. 791 - 794 (1997)
Update date:2022-08-10
Topics:
Crouch, R. David
Mitten, Jeffrey V.
Span, Amelia R.
Dai, H. George
Alkyl enol ethers can be converted into the corresponding alcohols in good to excellent yields by treatment with aqueous Hg(OAc)2 - NaBH4 in one reaction flask. This method is sufficiently mild to allow the survival of acid-sensitive groups such as silyl ethers, THP-protected alcohols and N-Boc-protected amines.
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