Tetrahedron Letters p. 1915 - 1916 (1986)
Update date:2022-07-31
Topics:
Tsuboi, Sadao
Nishiyama, Emiko
Utaka, Masanori
Takeda, Akira
Optically pure (R)-(-)-hexahydromandelic acid has been prepared stereoselectively in two steps by the asymmetric reduction of ethyl α,2-dioxocyclohexaneacetate with fermenting baker's yeast followed by Clemmensen reduction.
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