Enantioselective Preparation of α-Acyloxy Ketones from α-Hydroxy and α-Amino Acids

Article abstract of DOI:10.1016/0040-4039(95)01289-T

Various chiral α-acyloxy ketones have been easily prepared, in high yields with an excellent enantiomeric purity, by acylation of organomanganese reagents with the corresponding α-acyloxy carboxylic acid chlorides prepared from α-hydroxy and α-amino acids.