Tetrahedron Letters p. 2295 - 2298 (1986)
Update date:2022-08-16
Topics:
Thanupran, Chatchai
Thebtaranonth, Chachanat
Thebtaranonth, Yodhathai
The consecutive Michael addition of a nucleophile to an α-methylene cyclopentenone, thence to methyl acrylate, occurs readily and stereospecifically, yielding bicyclo-<2,2,1>-heptanone.The reaction represents the first example of a three-component triple conjugate addition process.
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Doi:10.1021/ja01623a058
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(1986)Doi:10.1021/jm00389a003
(1987)Doi:10.1039/DT9860002433
(1986)Doi:10.1063/1.439169
(1980)Doi:10.1016/j.bmcl.2008.08.076
(2008)