Chemistry Letters p. 571 - 574 (1992)
Update date:2022-08-18
Topics:
Kuno, Hideyuki
Shibagaki, Makoto
Takahashi, Kyoko
Honda, Ichiro
Matsushita, Hajime
The lactonization of ω-hydroxy esters was carried out by catalysis with hydrous zirconium(IV) oxide.In the flow reaction system, ω-hydroxy esters were efficiently converted to give the corresponding lactones.In particular, it is noteworthy that heptanolide is obtained in good yield.In addition, it is possible to produce a large quantity of lactones in this catalyst system.
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