A facile one-pot cyanation of primary and secondary alcohols. Application of some new Mitsunobu reagents

DOI: 10.1016/S0040-4039(99)01509-9

Source and publish data:

Tetrahedron Letters p. 7355 - 7358 (1999)

Update date:2022-08-11

Topics:

Authors:

Tsunoda, Tetsuto

Uemoto, Kaori

Nagino, Chisato

Kawamura, Megumi

Kaku, Hiroto

Ito, Sho

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(99)01509-9

Some new Mitsunobu reagents, especially N,N,N',N'-tetramethylazodicarboxamide(TMAD)-tributylphosphine (TBP) and cyanomethylenetrimethylphosphorane (CMMP), mediated the direct transformation of primary and secondary alcohols into the corresponding nitriles in the presence of acetone cyanohydrin. This type of cyanation process can convert 3β-cholestanol to 3α-cyanocholestane in high yield with complete Walden inversion.

Full text of DOI:10.1016/S0040-4039(99)01509-9

Products guided by the article

Product name:2-Methyl-1,8-octanediol

Cas No:109359-36-6

R&D Labs maybe for 109359-36-6

Shanxi Tongji Pharmaceuticals Co., Ltd.

Contact:+86-359-3024784

Address:Xikuang South Road, Ruicheng County , Shanxi
SJZ Chenghui Chemical Co., Ltd.

Contact:86-311-87713916

Address:no.368 youyi north avenue
Nanjing Duly Biotech Co., Ltd

website:http://www.dulynet.com/

Contact:025-84699383 -8003

Address:Room 503, Building 2, Chuangxinhui, No. 61 Wenjing Road, High-tech Development Zone, Pukou District, Nanjing City, Jiangsu Province Nanjing, Jiangsu
Hangzhou Yanshan Chemical Co.,Ltd.

Contact:86-571- 87698076

Address:Room 1001, #1 Building, Zhongtian MCC, No.2 Youzhinong, Wenyi West Road, Xihu District, Hangzhou, China
RongCheng K&S Chemical Co.,Ltd

Contact:0631-7336369

Address:rongcheng ,shandong province china

Relevant to this article

Pd/Mn Bimetallic Relay Catalysis for Aerobic Aldoxime Dehydration to Nitriles

Doi:10.1002/adsc.201701154
(2018)
Synthesis of Pyrano[2,3-d]pyrimidine-2,4-diones and Pyridino[2,3-d]pyrimidine-2,4,6,8-tetraones: Evaluation Antitumor Activity

Doi:10.1002/jhet.3830
(2020)
Iron phthalocyanine as new efficient catalyst for catalytic transfer hydrogenation of simple aldehydes and ketones

Doi:10.1002/aoc.3247
(2015)
One-step cross-coupling reaction of functionalized alkyl iodides with aryl halides by the use of an electrochemical method

Doi:10.1016/S0040-4020(99)00281-1
(1999)
Efficient desymmetrization of 1,2 and 1,3 diols by dimethyldioxirane

Doi:10.1016/0040-4039(95)00419-D
(1995)
Hexagonal nanoplates of NiO/CoO/Fe₂O₃ composite acting as an efficient photocatalytic and electrocatalytic water oxidation catalyst

Doi:10.1039/c5dt02046h
(2015)

Article Doi