New Hydroxyquinoline-Based Derivatives as Potent Modulators of Amyloid-β Aggregations

DOI: 10.1002/ardp.201500453

Source and publish data:

Archiv der Pharmazie p. 327 - 341 (2016)

Update date:2022-08-25

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Authors:

Fu, Chin-Lan

Hsu, Li-Shin

Liao, Yung-Feng

Hu, Ming-Kuan

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Article abstract of DOI:10.1002/ardp.201500453

Copper and zinc have been found to contribute to the burden of amyloid-β (Aβ) aggregations in neurodegenerative Alzheimer's disease (AD). Dysregulation of these metals leads to the generation of reactive oxygen species (ROS) and eventually results in oxid

Full text of DOI:10.1002/ardp.201500453

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