STERIC EFFECTS IN THE REACTION OF DI(BROMOMAGNESIO)ALKANES WITH CARBOXYLIC ESTERS

Article abstract of DOI:10.1016/S0040-4039(01)92402-5

Largely different product distributions were observed on the action of various carboxylic esters with 1,4-di(bromomagnesio)butane and its homologue 1,5-di(bromomagnesio)pentane.The much larger yields of reduction product with the latter are the evidence for the structural geometric requirements for the annelation step.