Regioselective Ni(II)-assisted alkylation of 2-methoxy-5,6- dihydro-2H-pyran: A new route to 2-n.alkyl-5,6-dihydro-2H-pyrans

DOI: 10.1016/S0040-4039(98)00162-2

Source and publish data:

Tetrahedron Letters p. 2025 - 2026 (1998)

Update date:2022-08-17

Topics:

Authors:

Guagnano, Vito

Lardicci, Luciano

Malanga, Corrado

Menicagli, Rita

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Article abstract of DOI:10.1016/S0040-4039(98)00162-2

In the presence of a catalytic amount of NidppeCl2, 2-methoxy- 5,6-dihydro-2H-pyran reacts with primary Grignard reagents to give the corresponding 2-n.alkyl-5,6-dihydro-2H-pyrans in satisfactory yields.

Full text of DOI:10.1016/S0040-4039(98)00162-2

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