Bioorganic and Medicinal Chemistry Letters p. 469 - 472 (1997)
Update date:2022-08-30
Topics:
Gobbini, Mauro
Benicchio, Alessandra
Padoani, Gloria
Torri, Marco
Melloni, Piero
The synthesis and the binding affinities to the digitalis receptor on the Na+, K+-ATPase of a series of 3β-(aminoalkylthio digitalis derivatives are described. In most cases these derivatives showed a higher binding affinity than that of the corresponding 3β-hydroxy and 3β-mercapto parent compounds.
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