Preparation of Tetrahydropyran Derivatives with α-Electron-Withdrawing Substituents from 1,5-Dibromopentane Derivatives by Treatment with Silver Nitrate

Article abstract of DOI:10.1246/cl.1987.333

When 1,5-dibromopentane derivatives having the electron-withdrawing groups at one terminus, wich were obtained by Cu(I)-catalyzed photochemical addition of 1,3-dibromopropanes to electron-deficient olefins, were subjected to treatment with silver nitrate, tetrahydropyran derivatives with the electron-withdrawing groups at the α-position to the oxygen atom were obtained.