
Tetrahedron p. 2895 - 2904 (1989)
Update date:2022-08-16
Topics:
Bonini, Carlo
Fabio, Romano Di
Sotgiu, Giovanni
Cavagnero, Silvia
The straightforward reductive opening of 1,2 epoxides to alcohols was studied and applied to several significant compounds.The reaction, which proceeds via the nucleophilic opening of the oxirane ring and the subsequent free radical dehalogenation, shows an excellent chemical yield as well as chemo and regioselectivity.This reaction was also applied to a chiral α,β-epoxyester.
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Doi:10.1039/c7cc04100d
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