Journal of Organic Chemistry p. 5433 - 5439 (2016)
Update date:2022-08-24
Topics:
Li, Liang
Wang, Jun-Jie
Wang, Guan-Wu
The first solvent-free manganese(III) acetate-promoted reaction of benzothiazole/thiazole derivatives with organophosphorus compounds including phosphine oxides, phosphinate ester, and phosphonate diester has been efficiently developed under ball-milling conditions, providing a highly efficient and green protocol to structurally diverse C2-phosphonylated benzothiazole/thiazole derivatives with remarkable functional group tolerance and excellent yields.
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