European Journal of Medicinal Chemistry p. 53 - 63 (2018)
Update date:2022-08-29
Topics:
Han, Tong
Tian, Kangtao
Pan, Huaqi
Liu, Yongxiang
Xu, Fanxing
Li, Zhanlin
Uchita, Takahiro
Gao, Ming
Hua, Huiming
Li, Dahong
A series of novel conjugates of brefeldin A (11a?c, 12a?c and 13a?c) were obtained by introducing a variety of nitrogen mustards at 4-OH or 7-OH position to explore more efficacious and less toxic antitumor agents. The antiproliferative activities were te
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