A novel method for preparation of trifluoromethyl substituted 2,3- dihydro-1,4-diazepine and benzimidazole

Article abstract of DOI:10.1080/00397910008087370

Ethylenediamine reacted readily with 4-ethoxy-1,1,1-trifluoro-3-butene- 2-one to form 5-trifluoromethyl-2,3-dihydro-1,4-diazepine in good yield. Under the same reaction conditions o-phenylene diamine gave 2-trifluoromethyl benzimidazole and benzimidazole.

Full text of DOI:10.1080/00397910008087370

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Synthetic Communications: An
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A Novel Method for Preparation
of Trifluoromethyl Substituted
2,3-dihydro-1,4- diazepine and
Benzimidazole
Qianli Chu a , Yanli Wang a & Shizheng Zhu a
a Shanghai Institute of Organic Chemistry, Chinese
Academy of Sciences, 354 Fenglin Road, Shanghai,
200032, P.R., China
Version of record first published: 04 Dec 2007.
To cite this article: Qianli Chu , Yanli Wang & Shizheng Zhu (2000): A Novel Method
for Preparation of Trifluoromethyl Substituted 2,3-dihydro-1,4- diazepine and
Benzimidazole, Synthetic Communications: An International Journal for Rapid
Communication of Synthetic Organic Chemistry, 30:4, 677-687
To link to this article: http://dx.doi.org/10.1080/00397910008087370
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