REACTIONS OF SOME D-RIBONOLACTONE DERIVATIVES WITH ALKYL CUPRATES. SYNTHESIS OF (+)-ELDANOLIDE AND (+)-TRANS-COGNAC LACTONE.

Article abstract of DOI:10.1016/S0040-4020(01)90327-8

Reactions of some D-ribonolactone derivatives with alkyl cuprates have been investigated in order to obtain molecules with a (4S,5R)-4,5-dialkyldihydro-2(3H)-furanone type constitution.As a direct application, (+)-eldanolide and (+)-trans-cognac lactone have been synthesized.