Elongation of the side chain by linear alkyl groups increases the potency of salacinol, a potent α-glucosidase inhibitor from the Ayurvedic traditional medicine “Salacia,” against human intestinal maltase

Article abstract of DOI:10.1016/j.bmcl.2020.127751

Four chain-extended analogs (12a–12d) and two related de-O-sulfonated analogs (13a and 13c) by introducing alkyl groups (a: R = C₃H₇, b R = C₆H₁₃, c: R = C₈H₁₇, d: R = C₁₀H₂