A New Synthetic Route to Perfluoroalkylidene-α,ο-Biisphosphonates

Article abstract of DOI:10.1016/0040-4039(94)02266-E

The UV irradiation of a mixture of (EtO)2POP(OEt)2 and I(CF2)nI (n = 3,4,6) or I(CF2)nP(O)(OEt)2 (n = 1,2) results in the corresponding bisphosphonites or mixed phosphonitephosphonates, respectively, which on oxidation by Me3COOH afforded the perfluoroalkylidene-α,ο-bisphosphonates in 64-77 percent isolated yields.