Extremely mild reagent for Boc deprotection applicable to the synthesis of peptides with thioamide linkages

DOI: 10.1039/cc9960002509

Source and publish data:

Chemical Communications p. 2509 - 2510 (1996)

Update date:2022-08-30

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Authors:

Frank, Robert

Schutkowski, Mike

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Article abstract of DOI:10.1039/cc9960002509

SnCl₄ in organic solvents acts as an extremely mild reagent for Boc deprotection even in the presence of the acid-labile thioamide moiety with excellent yields.

Full text of DOI:10.1039/cc9960002509

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