THE PROTECTION OF 2'-HYDROXY FUNCTIONS IN OLIGORIBONUCLEOTIDE SYNTHESIS

DOI: 10.1016/S0040-4039(01)81352-6

Source and publish data:

Tetrahedron Letters p. 3015 - 3018 (1984)

Update date:2022-08-11

Topics:

Authors:

Norman, G. David

Reese, B. Colin

Serafinowska, T. Halina

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(01)81352-6

The suitability of the 4-methoxytetrahydropyran-4-yl group for the protection of 2' ( or 3')-hydroxy functions in oligoribonucleotide synthesis is confirmed; the latter protecting group is removed in 0.01M-hydrochloric acid at room temperature under conditions which, contrary to a recent report, lead to no detectable cleavage or migration of the internucleotide phosphodiester linkages.

Full text of DOI:10.1016/S0040-4039(01)81352-6

Products guided by the article

Product name:Guanosine

Cas No:118-00-3

R&D Labs maybe for 118-00-3

Tianjin Ji Ping Jia Chemical Co., Ltd.

Contact:18622448868

Address:tianjin
Xi'an Tizan Tech & Industry Co., Ltd.

Contact:86-18629066522

Address:C3009 TANG FENG INTERNATIONAL PLAZA, NO.18 FENGHUI NAN ROAD, XI'AN HIGH TECH ZONE, 710075 CHINA.
Shanghai shibo Chemical Co., Ltd

Contact:+86-021-60753516

Address:688 Qiushi Road, Jinshan High-tech Park, Shanghai, China,201512
GIHI CHEMICALS CO.,LIMITED

Contact:+86-571-86217390

Address:No.567 Dengcai Street,Sandun,Westlake District,Hangzhou310030,Zhejiang,China.
Tianjin Derchemist Sci-Tech Co., Ltd.

website:http://www.derchemist.com

Contact:+86-22-58627059

Address:Xinmao Science and Technology Park，Huayuan Industrial Park

Relevant to this article

Carbon Nitride Supported High-Loading Fe Single-Atom Catalyst for Activation of Peroxymonosulfate to Generate ¹O₂ with 100 % Selectivity

Doi:10.1002/anie.202109488
(2021)
Pd/Cu-free Heck and Sonogashira cross-coupling reaction by Co nanoparticles immobilized on magnetic chitosan as reusable catalyst

Doi:10.1039/c6gc03377f
(2017)
Asymmetric Counter-Anion-Directed Aminomethylation: Synthesis of Chiral β-Amino Acids via Trapping of an Enol Intermediate

Doi:10.1021/jacs.8b12832
(2019)
N-Alkyl Imidazoles as Effective Axial Ligands in the Aerobic Asymmetric Epoxidation of Unfunctionalized Olefins Catalyzed by Optically Active Manganese(III)-salen-type Complex

Doi:10.1246/cl.1994.527
(1994)
Fe₃O₄–cysteamine hydrochloride magnetic nanoparticles: New, efficient and recoverable nanocatalyst for Knoevenagel condensation reaction

Doi:10.1002/aoc.3795
(2017)
Doi:10.1039/C39720001202
(1972)

Article Doi