Molecules (2016)
Update date:2022-08-18
Topics:
Park, Sunhwa
Lee, Jiyun
Shin, Kye Jung
Seo, Jae Hong
Aspirination of α-aminoalcohol (sarpogrelate M1) has been performed under various general esterification conditions. In most cases, the desired aspirinate ester was obtained at a low yield with unexpected byproducts, the formation of which was mostly derived from the chemical properties of the tertiary α-amino group. After systematic analysis of those methods, the aspirinated sarpogrelate M1 was prepared using a two-step approach combining salicylate ester formation and acetylation.
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Doi:10.1016/j.ica.2011.10.001
(2012)Doi:10.1021/ja00443a006
(1977)Doi:10.1021/jo00115a038
(1995)Doi:10.1021/tx0600595
(2006)Doi:10.1246/cl.1999.963
(1999)Doi:10.1007/BF00574575
(1986)
