Direct synthesis of Boc protected (D,L)-amino acids from Boc-glycine

DOI: 10.1016/S0040-4039(00)79015-0

Source and publish data:

Tetrahedron Letters p. 6461 - 6464 (1992)

Update date:2022-08-11

Topics:

Authors:

De Nicola

Einhorn Einhorn

Luche Luche

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Article abstract of DOI:10.1016/S0040-4039(00)79015-0

Boc-glycine is easily deprotonated by lithium diisopropylamide, yielding a trianion which is trapped with an electrophile to give access to Boc-(D,L)-amino acids.

Full text of DOI:10.1016/S0040-4039(00)79015-0

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