The novel syntheses of α-trifluoromethylated ketones from β-bromoenol phosphates

Article abstract of DOI:10.1080/10426500108040244

A series of 1-aryl-3,3,3-trifluro-1-propanones have been synthesized from the reaction of FO₂SCF₂CO₂Me wilh β-bromoenol phosphates in the presence of Cul in moderate yield. The reaction mechanism was discussion, the electron-withdrawing substituent at the β-position of the enol phosphates promoted the catalytic cleavage of the O-P bond in enol phosphates by fluoride ion.

Full text of DOI:10.1080/10426500108040244

This article was downloaded by: [University of Otago]
On: 19 July 2015, At: 23:46
Publisher: Taylor & Francis
Informa Ltd Registered in England and Wales Registered Number: 1072954
Registered office: 5 Howick Place, London, SW1P 1WG
Phosphorus, Sulfur, and Silicon
and the Related Elements
Publication details, including instructions for
authors and subscription information:
http://www.tandfonline.com/loi/gpss20
THE NOVEL SYNTHESES OF
α-TRIFLUOROMETHYLATED
KETONES FROM β-BROMOENOL
PHOSPHATES
Xiaogen Huang a , Yantao He a & Yixiang Ding a
a Shanghai Institute of Organic Chemistry, Chinese
Academy of Sciences , 354 Fenglin Road, Shanghai,
200032, China
Published online: 04 Oct 2006.
To cite this article: Xiaogen Huang , Yantao He & Yixiang Ding (2001) THE NOVEL
SYNTHESES OF α-TRIFLUOROMETHYLATED KETONES FROM β-BROMOENOL PHOSPHATES,
Phosphorus, Sulfur, and Silicon and the Related Elements, 174:1, 201-207, DOI:
10.1080/10426500108040244
To link to this article: http://dx.doi.org/10.1080/10426500108040244
PLEASE SCROLL DOWN FOR ARTICLE
Taylor & Francis makes every effort to ensure the accuracy of all the
information (the “Content”) contained in the publications on our platform.
However, Taylor & Francis, our agents, and our licensors make no
representations or warranties whatsoever as to the accuracy, completeness,
or suitability for any purpose of the Content. Any opinions and views
expressed in this publication are the opinions and views of the authors, and
are not the views of or endorsed by Taylor & Francis. The accuracy of the
Content should not be relied upon and should be independently verified with
primary sources of information. Taylor and Francis shall not be liable for any
losses, actions, claims, proceedings, demands, costs, expenses, damages,
and other liabilities whatsoever or howsoever caused arising directly or

indirectly in connection with, in relation to or arising out of the use of the
Content.
This article may be used for research, teaching, and private study purposes.
Any substantial or systematic reproduction, redistribution, reselling, loan,
sub-licensing, systematic supply, or distribution in any form to anyone is
expressly forbidden. Terms & Conditions of access and use can be found at
http://www.tandfonline.com/page/terms-and-conditions