Microwave-assisted aminolysis of vinylepoxides

DOI: 10.1016/S0040-4039(99)01811-0

Source and publish data:

Tetrahedron Letters p. 9273 - 9276 (1999)

Update date:2022-08-18

Topics:

Authors:

Lindstroem, Ulf M.

Olofsson, Berit

Somfai, Peter

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Article abstract of DOI:10.1016/S0040-4039(99)01811-0

Di- and trisubstituted vinylepoxides in NH₄OH were subjected to microwave irradiation affording the corresponding vicinal aminoalcohols in high yields. The reaction is stereospecific and highly regioselective for addition at the allylic carbon.

Full text of DOI:10.1016/S0040-4039(99)01811-0

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