Pressure and pH dependence of the kinetics of decarboxylative dechlorination of N-chloro-1-alanine

Article abstract of DOI:10.1002/(SICI)1097-4601(1996)28:11<791::AID-KIN1>3.0.CO;2-I

The kinetics of decarboxylative dechlorination of N-chloroalanine were studied at 25° in aqueous HCl solutions covering the pH range 1.4 to 2.8. These data were compared with literature results, and were interpreted in terms of first-order reactions of the cationic, uncharged, and anionic forms of the reactant. Pressure effect studies on the reaction of the anionic species yielded a volume of activation estimate of +50±3 cm³ mol^-1. This result is consistent with a concerted fragmentation process.