Tetrahedron Letters p. 3697 - 3698 (1999)
Update date:2022-08-24
Topics:
Flaih, Nazar
Pham-Huy, Chuong
Galons, Herve
Trifluoroacetamide was reacted with diacids in the presence of N-ethyl- N-dimethylaminopropylcarbodiimide and of 1-hydroxybenzotriazole to afford cyclic imides of different ring size, providing a single step asymmetric synthesis of thalidomide.
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