Tetrahedron Letters p. 3625 - 3628 (1989)
Update date:2022-08-17
Topics:
Fang, Francis G.
Prato, Maurizio
Kim, Guncheol
Danishefsky, Samuel J.
Annulation of diazomethylvinylketone (4a) with a variety of secondary thiolactams provides a novel route to dihydro-γ-pyridones.This approach has been applied to the synthesis of iso-A58365A (2), the γ-pyridone analog of the ACE inhibitor, A58365A (1).
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(1990)
