A SIMPLE AND EFFICIENT ONE POT SYNTHESIS OF 4-OXO-SPIRO AND THEIR REACTIONS WITH DDQ

Article abstract of DOI:10.3987/COM-95-7225

The treatment of two equivalents of the anion of 3,4-dihydro-1H-quinoline-2-thione (3) with one equivalet of one of the N-substituted 2-bromoacetamides (4a-d) at room temperature afforded the title compounds in good yields (Scheme 1, Table 1).The reaction of the compounds (6a-d) with DDQ at room temperature and 90 deg C was studied.Mechanistic aspects of the processes are briefly discussed.