Tetrahedron Letters p. 3629 - 3632 (1980)
Update date:2022-08-04
Topics:
Kashman
Groweiss
Shmueli
Three new toxins were isolated from the Red Sea sponge Latrunculia magnifica A full structure determination of these toxins, by spectroscopic methods, was aided by an X-ray diffraction analysis of a crystalline derivative (1b) of latrunculin-A. The Latrunculins exhibit a new class of 14 and 16 membered macrolides to which the rare 2-thiazolidinone moiety is attached. A biogenesis of these biologically active compounds is put forward.
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