Efficient diastereoselective synthesis of anti-α-bromo-β-hydroxyketones

DOI: 10.1016/S0040-4039(99)01640-8

Source and publish data:

Tetrahedron Letters p. 7875 - 7877 (1999)

Update date:2022-08-31

Topics:

Authors:

Brown, Herbert C.

Zou, Mu-Fa

Ramachandran, P. Veeraraghavan

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Article abstract of DOI:10.1016/S0040-4039(99)01640-8

Anti-α-bromo-β-hydroxyketones were synthesized in high diastereoselectivity via the enolboration of a representative series of bromomethylketones using dicyclohexylboron chloride, followed by aldolization with aldehydes.

Full text of DOI:10.1016/S0040-4039(99)01640-8

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