Synlett p. 378 - 380 (1997)
Update date:2022-07-31
Topics:
Yannopoulos, Constantin G.
Zhou, Wen-Qiang
Nower, Peter
Peoc'h, Didier
Sanghvi, Yogesh S.
Just, George
Syntheses of three novel conformationally rigid dimers containing cyclopropyl -amide and -sulfonamide functionalities are described. Their incorporation into an oligonucleotide sequence resulted in considerable lowering of the Tm's in binding to their complementary RNA sequences.
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