Research on Chemical Intermediates p. 5399 - 5407 (2019)
Update date:2022-08-11
Topics:
Pallikonda, Gangaram
Hsieh, Chang-Yu
Su, Haw-Lih
Hsieh, Jen-Chieh
Three related alkaloids, oxynitidine, nitidine and 5,6-dihydronitidine, have been afforded by the new synthetic protocols. In this approach, the Ni-catalyzed annulation reaction is indicated as the key step to construct the isoquinolinone core structure. The subsequent transformations lead to the target alkaloids.
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