Bioorganic and Medicinal Chemistry Letters p. 1397 - 1402 (1999)
Update date:2022-08-11
Topics:
Vieira, Eric
Binggeli, Alfred
Breu, Volker
Bur, Daniel
Fischli, Walter
Gueller, Rolf
Hirth, Georges
Maerki, Hans Peter
Mueller, Marcel
Oefner, Christian
Scalone, Michelangelo
Stadler, Heinz
Wilhelm, Maurice
Wostl, Wolfgang
The identification, synthesis and activity of a novel class of piperidine renin inhibitors is presented. The most active compounds show activities in the picomolar range and are among the most potent renin inhibitors ever identified.
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