Heterocyclic Communications p. 415 - 418 (2005)
Update date:2022-08-16
Topics:
Abaee, M. Saeed
Sharifi, Ruhollah
Borhani, Shahin
Heravi, Majid M.
Motahari, Hossein
A one pot synthetic strategy for the preparation of fluoroquinolones from 1 is introduced. Product 3 was condensed with piperazine in an aqueous media to produce pharmaceutical grade ciprofloxacin in 86% yield. The method was extended to the synthesis of some other fluoroquinolones with pharmaceutical grade quality.
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