C,C-Coupling with sulfur-stabilized carbanions - 6. Preparation and electrophilic substitution of 1-[3-methyl-2-(2-thioanylthio)-butyl]piperidine and dethioacetalization of semicyclic dithioacetals

Article abstract of DOI:10.1016/0040-4020(96)00757-0

1-[3-Methyl-2-(2-thioanylthio)butyl]piperidine (8) is obtained from L-valine via enantiomerically pure 1-(2-mercapto-3-methylbutyl)piperidine (6). The diastereoisomers are separated by column chromatography and the reactions of the carbanion 8a with elect