Synthetic Communications p. 799 - 806 (2005)
Update date:2022-08-29
Topics:
Gohier, Frederic
Castanet, Anne-Sophie
Mortier, Jacques
2-Chloro-6-substituted benzoic acids of the type 2a-h were prepared by the tandem metallation sequence from 2-chlorobenzoic acid 1 with the 1:1 complex secbutyllithium/TMEDA in THF at -78°C followed by quenching with electrophiles.
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