Chemical and Pharmaceutical Bulletin p. 1378 - 1381 (1991)
Update date:2022-08-16
Topics:
Kayakiri
Takase
Shibata
Hashimoto
Tada
Koda
The structure of kifunensine, a new immunomodulator produced by a strain of Kitasatosporia, has been established as 1 on the basis of chemical and physicochemical evidence and X-ray crystallographic analysis. Kifunensine is unique both in its novel structure, containing a 4,5-dioxoimidazolidine ring included in the bicyclic framework, and in its potent immunomodulating activity. It is a representative of a new class of 1,5-iminopyranoses.
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