Chemical and enzymatic synthesis and antiviral properties of 2'-deoxy- 2'-fluoroguanosine

Article abstract of DOI:10.1080/15257779908041541

Chemical and enzymatic methods were employed for the synthesis of the title compound, 2'F-Guo 7. High antiviral activity of 2'F-Guo was established in chick embryo cells infected with influenza virus FPV/Rostock/34 (H7N1) and herpes simplex virus (HSV) type I (1C strain).

Full text of DOI:10.1080/15257779908041541

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Nucleosides and Nucleotides
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Chemical and Enzymatic Synthesis and
Antiviral Properties of 2′-Deoxy-2′-
fluoroguanosine
Galina V. Zaitseva a , Anatoli I. Zinchenko b , Vladimir N. Barai b , N.
I. Pavlova c , Evgeny I. Boreko c & Igor A. Mikhailopulo a
a Institute of Bioorganic Chemistry, National Academy of Sciences ,
Acad. Kuprevicha 5, 220141, Minsk, Belarus
b Institute of Microbiology, National Academy of Sciences , Acad.
Kuprevicha 2, 220141, Minsk, Belarus
c Byelorussian Research Institute of Epidemiology & Microbiology , K.
Zetkin 4, 220050, Minsk, Belarus
Published online: 04 Oct 2006.
To cite this article: Galina V. Zaitseva , Anatoli I. Zinchenko , Vladimir N. Barai , N. I. Pavlova ,
Evgeny I. Boreko & Igor A. Mikhailopulo (1999) Chemical and Enzymatic Synthesis and Antiviral
Properties of 2′-Deoxy-2′-fluoroguanosine, Nucleosides and Nucleotides, 18:4-5, 687-688, DOI:
10.1080/15257779908041541
To link to this article: http://dx.doi.org/10.1080/15257779908041541
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