Regiocontrol in the intramolecular silyl modified Sakurai (ISMS) reaction. An efficient synthesis of a Dacus oleae fruit fly pheromone

Article abstract of DOI:10.1016/S0040-4039(00)91736-2

The ISMS reaction, which initially afforded a mixture of regioisomeric olefins, can now be controlled to produce only the exocyclic alkene. The ISMS methodology was used in a highly efficient synthesis of a Dacus oleae pheromone 8.