Novel synthesis of a 2H-1,2-benzothiazine-1,1-dioxide derivative

Article abstract of DOI:10.1080/00397910008086996

We report a novel synthesis of 4-chloro-2-cyclohexyl-6,7-dimethoxy-2H-1,2-benzothiazine-1,1-dioxide 6 from 3,4-dimethoxychalcone 1. Chlorosulfonation of 1 followed by amination, then epoxidation under basic conditions with immediate elimination of the ben

Full text of DOI:10.1080/00397910008086996

This article was downloaded by: [University of Colorado at Boulder Libraries]
On: 19 December 2014, At: 18:22
Publisher: Taylor & Francis
Informa Ltd Registered in England and Wales Registered Number: 1072954
Registered office: Mortimer House, 37-41 Mortimer Street, London W1T 3JH,
UK
Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
Publication details, including instructions for
authors and subscription information:
http://www.tandfonline.com/loi/lsyc20
Novel Synthesis of a 2H-1,2-
Benzothiazine -1,1-Dioxide
Derivative
a
b
Jatinder P. Bassin , Martin J. Frearson & Karim Al-
a
Nawwar
a
Department of Chemistry , American University of
Beirut , Beirut, Lebanon
b
Department of Physical Sciences , University of
Hertfordshire , Hatfield, Herts, AL10 9AB, England
Published online: 04 Dec 2007.
To cite this article: Jatinder P. Bassin , Martin J. Frearson & Karim Al-Nawwar
(2000) Novel Synthesis of a 2H-1,2-Benzothiazine -1,1-Dioxide Derivative, Synthetic
Communications: An International Journal for Rapid Communication of Synthetic
Organic Chemistry, 30:20, 3693-3701, DOI: 10.1080/00397910008086996
To link to this article: http://dx.doi.org/10.1080/00397910008086996
PLEASE SCROLL DOWN FOR ARTICLE
Taylor & Francis makes every effort to ensure the accuracy of all the
information (the “Content”) contained in the publications on our platform.
However, Taylor & Francis, our agents, and our licensors make no
representations or warranties whatsoever as to the accuracy, completeness,
or suitability for any purpose of the Content. Any opinions and views
expressed in this publication are the opinions and views of the authors, and
are not the views of or endorsed by Taylor & Francis. The accuracy of the

Content should not be relied upon and should be independently verified with
primary sources of information. Taylor and Francis shall not be liable for any
losses, actions, claims, proceedings, demands, costs, expenses, damages,
and other liabilities whatsoever or howsoever caused arising directly or
indirectly in connection with, in relation to or arising out of the use of the
Content.
This article may be used for research, teaching, and private study purposes.
Any substantial or systematic reproduction, redistribution, reselling, loan,
sub-licensing, systematic supply, or distribution in any form to anyone is
expressly forbidden. Terms & Conditions of access and use can be found at
http://www.tandfonline.com/page/terms-and-conditions