Enhanced Li+ ion-selective ionophoric properties of double armed diaza-12-crown-4 derivatives

Article abstract of DOI:10.1016/S0040-4020(97)00082-3

A variety of double armed crown ether were prepared in which amine, amide, ester, nitrile and pyridine moieties were attached as cation-ligating sidearms to diaza-12-crown-4 ring. FAB-MS and ⁷Li/¹³C/²³Na NMR binding and liquid membrane transport studies revealed that mast of them exhibited Li⁺ cation selectivity, though corresponding single armed lariat ethers showed Na⁺ cation selectivity. Among them, amine-armed diaza-12-crown-4 derivative offered the highest Li⁺ ion-selective ionophoric property. its transport efficiency and selectivity were particularly superior to those of commercially available Li⁺ ion-selective ionophores.