Journal of Pharmaceutical Sciences p. 181 - 182 (1992)
Update date:2022-08-11
Topics:
Bosca
Miranda
Vargas
The phototoxic nonsteroidal anti-inflammatory drug tiaprofenic acid (1) is photolabile under aerobic conditions. Irradiation of a methanol solution of 1 under oxygen produces the photoproducts 2, 3, 4, and 5, and also produces a singlet oxygen as evidenced by trapping with 2,5-dimethylfuran.
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