ALKYLATION OF 2-METHYLTHIO-4-HYDROXYPYRIMIDINES BY METHYL BROMOACETATE

DOI: 10.1007/BF00479372

Source and publish data:

Chemistry of Heterocyclic Compounds p. 1216 - 1218 (1987)

Update date:2022-08-11

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Authors:

Vainilavichyus, P. I.

Syadyaryavichyute, V. Yu.

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Article abstract of DOI:10.1007/BF00479372

2-Methylthio-4-hydroxypyrimidines react with methylbromoacetate in methanol-sodium methoxide solution to give O- and N₍₃₎-alkylated products, namely, 2-methylthio-4-(methoxycarbonyl)methoxypyrimidines and 2-methylthio-3-(methoxycarbonyl)methylpyrimid-4-ones.

Full text of DOI:10.1007/BF00479372

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