Synthesis of a new exocyclic amino carbocyclic nucleoside with potential antiviral activity

Article abstract of DOI:10.1016/S0040-4039(00)73729-4

The total synthesis of a new exocyclic amino carbocyclic nucleoside, (±)-(1),(±)-1′(β)-[4-(6-amino-5- nitro)pyrimidine-amino-2′-(α)-hydroxy-4′- hydroxymethylcyclopentane has been accomplished. 1-Hydroxymethyl-3- cyclopentene has been converted into a carbocyclic nucleoside in six steps.