Bioorganic and Medicinal Chemistry Letters p. 2995 - 2996 (1998)
Update date:2022-08-11
Topics:
Ostaszewski, Ryszard
Wilczynska, Edyta
Wolszczak, Marian
A new type of DNA intercalator based on anthracene 3 was synthesized. Preliminary binding studies show high affinity of this probe to CT-DNA. Higher binding constant of this compound (4.0 x 104 M-1) as compared with that known for 9-aminomethylanthracene, is caused presumably by enhanced electrostatic interaction.
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Doi:10.1002/1522-2640(200008)72:8<858::AID-CITE858>3.0.CO;2-4
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