Asymmetric synthesis of (2R, 3S) and (2S, 3R) precursors of β-methyl-histidine, -phenylalanine and -tyrosine

Article abstract of DOI:10.1016/S0957-4166(00)80091-9

A systematic series of (2S, 3R) and (2R, 3S) precursors to β-methyl-histidine, -phenylalanine and -tyrosine, which are of significant importance in the design of peptide and protein ligands, have been synthesized in high optically purity and yield.