Synthesis of the isomers of dichlorodiammineplatinum(II) from the magnus salt

Article abstract of DOI:10.1134/S1070328406090120

The synthesis of the isomers of dichlorodiammineplatinum (II) from the Magnus salt is described. The Magnus salt is added to an aqueous solution of ammonium acetate. The reaction mixture is heated for an hour and then cooled. hydrochloric acid is added an

Full text of DOI:10.1134/S1070328406090120

ISSN 1070-3284, Russian Journal of Coordination Chemistry, 2006, Vol. 32, No. 9, p. 692. © Pleiades Publishing, Inc., 2006.
Original Russian Text © A.K. Starkov, V.I. Kazbanov, G.A. Kozhukhovskaya, A.G. Olado, 2006, published in Koordinatsionnaya Khimiya, 2006, Vol. 32, No. 9, p. 720.
LETTERS TO THE EDITOR
Synthesis of the Isomers of Dichlorodiammineplatinum(II)
from the Magnus Salt
†
A. K. Starkov, V. I. Kazbanov , G. A. Kozhukhovskaya, and A. G. Olado
Institute of Chemistry and Chemical Technology, Siberian Division, Russian Academy of Sciences, Krasnoyarsk, Russia
Received February 6, 2006
DOI: 10.1134/S1070328406090120
Complex compounds of potassium or ammonium
The salt trans-[Pt(NH ) Cl *] is used to prepare tet-
3 2 2
trichloroammineplatinate(II) are used as starting mate- raamminedichloroplatinum(II), which is employed in
rials in the synthesis of biologically active mixed plati- the synthesis of monoammineplatinum(II) compounds
num complexes of the second and third generations [1]. [6]. The salt cis-[Pt(NH ) Cl *] is used as a biologically
3
2
2
The synthesis of these complexes involves tetraam- active substance [1] and as the starting reagent for the
minedichloroplatinum(II) and potassium tetrachloro- synthesis of potassium or ammonium trichloroammine-
platinate(II) as subsidiary complexes, which are then platinate(II) [6].
removed from the reaction in the form of the insoluble
Magnus salt [Pt(NH ) ][PtCl ]. This salt is not
employed in subsequent synthesis of potassium or
ammonium trichloroammineplatinate(II), which sub-
stantially (by half) lowers the yields of the major prod-
ucts [2–5].
Thus, the proposed method provides substantial
increase in the yield of potassium or ammonium
trichloroammineplatinate(II) due to the use of platinum
from the Magnus salt.
3
4
4
REFERENCES
This study was devoted to the synthesis of the iso-
mers of dichlorodiammineplatinum(II) from the Mag-
nus salt.
1. Cleare, M.J., Coord. Nhem. Rev., 1974, vol. 12, no. 4,
p. 349.
2
3
. Jorgensen, J., Z. Anorg. Chem., 1890, vol. 24, p. 181.
The Magnus salt [Pt(NH ) ][PtCl ] was added to an
3
4
4
. Gel’man (Nikitina), A.D., Kompleksnye soedineniya
platiny s nenasyshchennymi molekulami (Complex
Compounds of Platinum with Unsaturated Molecules),
Moscow: Akad. Nauk SSSR, 1945, p. 96.
aqueous solution of ammonium acetate. The reaction
mixture was heated for an hour and then cooled. Hydro-
chloric acid was added and the resulting microcrystal-
*
line salt Pt(NH ) Cl was isolated in 80% yield. Heat-
3
2
2
4
5
6
. Gel’man, A.D., Karandasheva, E.F., and Essen, L.N., Izv.
Sektora Platiny I Dr. Blagorodnykh Metallov AN SSSR,
1949, no. 24, p. 60.
. Zheligovskaya, N.N., Dyakova, G.B., Fat’kin, A.Yu.,
and Bokareva, S.S., Koord. Khim., 1991, vol. 17, no. 10,
p. 1412.
. Sintez kompleksnykh soedinenii metallov platinovoi
gruppy (Synthesis of Complex Compounds of Platinum
Group Metals), Chernyaev, I.I., Ed., Moscow: Nauka,
1964.
ing was continued for 1.5 h. On cooling, trans*-
*
[
Pt(NH ) Cl ] was isolated in 78% yield. The isomers
3
2
2
of dichlorodiammineplatinum(II) were identified, and
their structures were proven, by elemental and X-ray
diffraction analyses, IR spectroscopy, and UV spectro-
photometry.
†Deceased.
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