Journal of Fluorine Chemistry p. 87 - 90 (1994)
Update date:2022-08-11
Topics:
Burger, Klaus
Rudolph, Martin
Fehn, Susanna
Sewald, Norbert
Syntheses for (2S)-4,4-difluoroproline, (2S,4R)-4-fluoroproline and their derivatives are described starting from (S)-aspartic acid, using hexafluoroacetone as the protecting reagent and DAST as the fluorinating agent.
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